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Posted by: thepinetree on 04/02/2020 08:39 PM Updated by: thepinetree on 04/02/2020 08:39 PM
Expires: 01/01/2025 12:00 AM
:

BAT Working on Potential COVID-19 Vaccine Through US Bio-Tech Subsidiary. Potential to Manufacture 1-3 Million Doses of Vaccine Per Week

Owensboro, KY...BAT’s US bio-tech subsidiary, Kentucky BioProcessing (KBP), is developing a potential vaccine for COVID-19 and is now in pre-clinical testing. If testing goes well, BAT is hopeful that, with the right partners and support from government agencies, between 1 and 3 million doses of the vaccine could be manufactured per week, beginning in June.





While KBP remains a commercial operation, the intention is that its work around the COVID-19 vaccine project will be carried out on a not for profit basis.

The vaccine in development uses BAT’s proprietary, fast-growing tobacco plant technology which has several advantages over conventional vaccine production technology:

It is potentially safer given that tobacco plants can’t host pathogens which cause human disease.
It is faster because the elements of the vaccine accumulate in tobacco plants much more quickly – 6 weeks in tobacco plants versus several months using conventional methods.

The vaccine formulation KBP is developing remains stable at room temperature, unlike conventional vaccines which often require refrigeration.
It has the potential to deliver an effective immune response in a single dose.
BAT’s US subsidiary, Reynolds American Inc, acquired KBP in 2014, with the aim of using some of its unique tobacco extraction technology to aid further development of its new category non-combustible products.

In 2014, KBP made headlines as one of the few companies with an effective treatment for Ebola, having manufactured ZMapp™ with California-based company Mapp BioPharmaceuticals in partnership with the U.S. Biomedical Advanced Research and Development Authority (BARDA).

KBP recently cloned a portion of COVID-19’s genetic sequence which led to the development of a potential antigen - a substance which induces an immune response in the body and in particular, the production of antibodies. This antigen was then inserted into tobacco plants for reproduction and, once the plants were harvested, the antigen was then purified, and is now undergoing pre-clinical testing.

BAT is now exploring partnerships with government agencies to bring its vaccine to clinical studies as soon as possible. Through collaborations with government and third-party manufacturers, BAT believes that between 1 and 3 million doses per week could be manufactured.

Dr David O’Reilly, Director of Scientific Research, BAT said: “We are engaged with the US Food and Drug Administration and are seeking guidance on next steps. We have also engaged with the UK’s Department for Health and Social Care, and BARDA in the US, to offer our support and access to our research with the aim of trying to expedite the development of a vaccine for COVID-19.

“Vaccine development is challenging and complex work, but we believe we have made a significant break-through with our tobacco plant technology platform and stand ready to work with Governments and all stakeholders to help win the war against COVID-19. We fully align with the United Nations plea, for a whole-of-society approach to combat global problems.

“KBP has been exploring alternative uses of the tobacco plant for some time. One such alternative use is the development of plant-based vaccines. We are committed to contributing to the global effort to halt the spread of COVID-19 using this technology.”

Tobacco plants used for vaccine development being cultivated at our KBP facilities.
Tobacco plants being cultivated for vaccine development at our KBP facilities.

Notes to Editors:
Currently this is a potential vaccine candidate, not a vaccine or a cure, given this is early stages of the development process. BAT has unrivalled knowledge and expertise of tobacco and hopes its subsidiary KBP can contribute to the cause.

About BAT: BAT is a leading, multi-category consumer goods business, established in 1902. Our purpose is to build A Better Tomorrow by reducing the health impact of our business through offering a greater choice of enjoyable and less risky products for our consumers. Our ambition is to increasingly transition our revenues from cigarettes to non-combustible products over time.

About Kentucky Bioprocessing (KBP): BAT owned KBP is located in Owensboro, Ky., where it began operations in 2006. In January 2014, KBP was acquired by and became an independently operated, wholly-owned subsidiary of Reynolds American Inc. (RAI), owned by BAT. KBP continues to house its large, multilevel indoor plant-growth space, as well as its research and production laboratories, clean rooms and manufacturing operations in Owensboro.

KBP develops and executes processes to transform tobacco plants into “biomanufacturing factories” that efficiently produce complex proteins they would not otherwise produce. The company can grow, harvest and process as many as 3 million protein-producing tobacco plants in a production cycle that typically takes about six weeks – compared with many months using traditional biomanufacturing methods.

The company uses licensed and proprietary technologies to temporarily encode tobacco plants with the genetic instructions to produce specific target proteins. The plants are grown in an automated, climate-controlled environment that can be adjusted to optimize their production of a protein of interest.

Forward looking statements
References to ‘British American Tobacco’, ‘BAT’, ‘we’, ‘us’ and ‘our’ when denoting opinion refer to British American Tobacco p.l.c. (the Company, and together with its subsidiaries, the “Group”).

This release contains certain forward-looking statements, including “forward-looking” statements made within the meaning of Section 21E of the United States Securities Exchange Act of 1934, regarding our intentions, beliefs or current expectations reflecting knowledge and information available at the time of preparation and concerning, amongst other things, prospects, growth, strategies and uncertainties related to regulatory approval and the results of pre-clinical testing. BAT undertakes no obligation to update or revise these forward-looking statements, whether as a result of new information, future events or otherwise. Readers are cautioned not to put undue reliance on such forward-looking statements.

These statements are often, but not always, made through the use of words or phrases such as “aim,” “believe,” “explore,” “anticipate,” “could,” “may,” “would,” “should,” “intend,” “plan,” “potential,” “predict,” “will,” “estimate,” “strategy” and similar expressions. It is believed that the expectations reflected in this release are reasonable but they may be affected by a wide range of variables that could cause actual results to differ materially from those currently anticipated, including uncertainties related to regulatory approval and the results of pre-clinical testing.


Comments - Make a comment
The comments are owned by the poster. We are not responsible for its content. We value free speech but remember this is a public forum and we hope that people would use common sense and decency. If you see an offensive comment please email us at news@thepinetree.net
No Subject
Posted on: 2020-04-02 20:49:21   By: Anonymous
 
How strange would it be if big tobacco saves the world from a respiratory illness?

[Reply ]

    Re:
    Posted on: 2020-04-03 07:47:31   By: Anonymous
     
    When are the leaders of the county fair going to take the bull by the horns and cancell this years event? Come on Lorrie, its time. Make a move!

    [Reply ]

      Re:
      Posted on: 2020-04-04 08:21:43   By: Anonymous
       
      It all boils down to money. They would have so much to reimburse everyone that has already paid. They are probably trying to figure out a way to not pay everyone back before they make the call. The one's I feel sorry for are the kids with animals. They have so much invested in their animals and are just investing more due to the delay. They need to make the call and cancel so at least the kids can try to sell their animals and recoup some of their money.

      [Reply ]

No Subject
Posted on: 2020-04-02 20:51:00   By: Anonymous
 
It this a paid for ad? Or just a freebee?

[Reply ]

    Re:
    Posted on: 2020-04-03 05:32:12   By: Anonymous
     
    What this is is complete BS. Any vaccine developed must undergo testing that takes 12-18 months before it's approved by the FDA for public use. The millions of doses supposedly available in June wouldn't be used on anyone.

    What is the point of posting this story?

    [Reply ]

      Re:
      Posted on: 2020-04-03 06:24:10   By: Anonymous
       
      It's called John Hamilton. TPT a propaganda machine. And local news my ass. More like let me masturbate in my robe to all my cult following brainless, derogatory commentators.

      [Reply ]

        Re:
        Posted on: 2020-04-03 09:29:42   By: thepinetree
         
        We posted this because this was one of the primary development techniques in battling ebola. The primary interest of this piece is that they can rapidly manufacture large quantities of a vaccine if and when one is developed.

        [Reply ]

VACCINE
Posted on: 2020-04-03 07:40:17   By: Anonymous
 
This should be a national priority. Having an effective and safe vaccine
should be a Federal Priority. It will be the end of the COVID-19
epidemic. It will probably take 18 months.
Being hopeful and optimistic is good.

[Reply ]

    Gene Splicing- GMO
    Posted on: 2020-04-03 09:07:55   By: Anonymous
     
    The vaccine would be a GMO.
    GMOs are produced by gene splicing, DNA is inserted into a cross species gene sequence. This does not occur in nature.
    There are many examples of this technology, the widely known , the Round-Up ready crops of corn, soy, alfalfa , used this technology to make the crops resistant to Round-Up herbicide.
    RR technology involves inserting cross DNA of an algae that was found in a tank of Round-Up that the herbicide did not kill. The DNA of this algae was then inserted into soy first, then other crops. This is why farmers can use Round-Up on RR crops, and not kill the crops. The problem is nature has natural selection, no species have the same dna, and immune structures, why the black plague didn't kill all in Europe, and also why some people do not show any signs of Covid-19, others are killed.
    With RR crops super weeds evolved because of natural selection, so now the farmers must change herbicides to get weed control, Nature is very adaptable.


    [Reply ]

No Subject
Posted on: 2020-04-03 09:08:02   By: Anonymous
 
Too bad this same effort hasn’t been put forward, finding a cure for cancer! My grandmother had breast cancer in 1958, I was11, I am now 72, 61 yrs. have past and guess what, no cure! Not to mention the death of my wife a millions more from cancer! Someone sitting on the cure? Heaven help you if you are!

[Reply ]

    Re:
    Posted on: 2020-04-03 09:31:23   By: Anonymous
     
    I have been saying this for years. We have been generously donating money to the American Cancer Society for as long as I can remember and yet not a single cure, I am now 63 years old and more people are dying from cancer than ever before. How is this possible...

    [Reply ]

      Actually...
      Posted on: 2020-04-03 14:14:02   By: Anonymous
       
      Cancer death rates have dropped for most all cancers. Fact.
      Detection annual physicals are important.
      The ACA gives you these at no cost.
      Unfortunately tRump is denying opening open enrollment for this affordable healthcare tRump is a sociopath. He does not care if people die..

      [Reply ]

        Re: Actually...
        Posted on: 2020-04-03 15:08:20   By: Anonymous
         
        The flat landers did it☢️

        [Reply ]

No Subject
Posted on: 2020-04-03 16:54:36   By: Anonymous
 
I pooped in your pants today, is that Trumps fault also?

[Reply ]

    Re: American Cancer Society
    Posted on: 2020-04-05 08:21:00   By: Anonymous
     
    The American Cancer Society has been in existence since 1913, 107 years and you blame their inadequacy on President Trump in office for the past three years. Early detection has always been known as the best chance of surviving cancer, we don't need a money hog like ACS to tell us this. Liberals response to everything is to make it political, amazing. The following is a quote from the ACS. "The American Cancer Society raises well over $1 billion each year. Of that, 15 percent goes to pay for fund raising activities, and roughly 60 percent goes to pay salaries and benefits for the organization's employees". So who is benefiting from this?

    [Reply ]


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